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Table of Contents > Drug > Immune Globulin Print

Immune Globulin

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Carimune® NF;Flebogamma® DIF;GamaSTANT S/D;Gammagard S/D®;Gammagard® Liquid;Gammaplex®;Gamunex® [DSC];Gamunex®-C;Hizentra®;Octagam®;Privigen®;Vivaglobin® [DSC]
    • Brand Names: Canada: BayGam®;Gamimune® N;Gammagard Liquid;Gammagard S/D;Gamunex®;IGIVnex®;Privigen®;Vivaglobin®
    • Pharmacologic Category: Blood Product Derivative;Immune Globulin

    Uses
    • It is used to stop or lower the harshness of other infections in people with a weak immune system.
    • It is used to treat idiopathic thrombocytic purpura (ITP).
    • It is used treat chronic inflammatory demyelinating polyneuropathy (CIDP).
    • It is used to stop or lower the harshness of infection by hepatitis A, measles, chickenpox (varicella), and rubella.
    • Immune globulin helps the body fight infection.
    • It helps platelets live longer.
    • It lowers swelling.

    Dosing

    How to take

    • It is given as a shot into a muscle, vein, or into the fatty part of the skin.
    • SubQ:
    • It is given as an infusion under the skin over a period of time.
    • Your doctor may teach you how to give this drug.
    • Wash your hands before and after use.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • Call your doctor to find out what to do.

    Storage

    • Most of the time, this drug will be given to you in a doctor's office. You will not store it at home.
    • Hizentra®:
    • Store at room temperature. Do not freeze.
    • Gammagard® Liquid, Vivaglobin®:
    • Store in a refrigerator. Do not freeze.

    Safety



    Warnings

    • This drug may cause kidney problems in some patients. Talk with your doctor.
    • Immune globulin is made from human plasma (part of the blood) and may have viruses that may cause disease. This drug is screened, tested, and treated to lower the chance that it carries an infection. Talk with your doctor.

    Avoid

    • If you have an allergy to immune globulin or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have a latex allergy, talk with your doctor.
    • If you have any of these health problems: A bleeding or blood clotting problem or IgA deficiency.
    • I.M.
    • If you have low platelet levels.
    • Gammaplex®, Hizentra®:
    • If you are allergic to polysorbate 80.
    • Hizentra®, Privigen®:
    • If you have too much proline in your blood (hyperprolinemia).

    Precautions

    • If you are 65 or older, use this drug with care. You could have more side effects.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of a very bad infection or make the vaccine not work as well.
    • If you have had blood clots, talk with your doctor.
    • If you have fluid loss, talk with your doctor.
    • If you have high blood sugar (diabetes), talk with your doctor.
    • If you have heart disease, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have had a stroke, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Irritation where the shot is given.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Headache.
    • Loose stools.
    • Belly pain.
    • Feeling tired or weak.
    • Back pain.
    • Cough.
    • Sore throat.
    • High blood pressure.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Trouble breathing.
    • Chest pain.
    • Feeling very tired or weak.
    • Very bad headache.
    • Very upset stomach or throwing up.
    • A big weight gain.
    • Swelling or pain in the leg or arm.
    • Sudden change in eyesight, eye pain, or irritation.
    • Not able to pass urine.
    • Neck stiffness.
    • Seizures.
    • Dark urine or yellow skin or eyes.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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